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[15] Primary spontaneous pneumothorax (PSP) has for many years been thought to be caused by "blebs" (small air-filled lesions just under the pleural surface), which were presumed to be more common in those classically at risk of pneumothorax (tall males) due to mechanical factors

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The American Lung Association has also issued a warning, stating e-cigarettes are not safe and can cause irreversible lung damage and lung disease. The FDA Has Serious Concerns About Vaping The US Food and Drug Administration (FDA) is currently looking into a possible link between e-cigarettes and seizures or other neurologic symptoms