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The FDAs action is a critical step in preventing the introduction of tobacco products that may be more appealing to youth, more addictive or more harmful, the group said in a statement

Various targeted sequencing panels have recently been developed to efficiently determine tumour mutation burden, and a strong correlation has been observed between targeted sequencing and whole genome sequencing in some studies.31 32 Another limitation of our study was recall bias, which cannot be ruled out when obtaining smoking information, even in a prospective cohort study

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