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According to a 2007 review published in the Annals of Hematology, both iron overload and iron-deficiency anemia can increase the risk of thrombosis and related cardiac events ( 5 )
Therefore, it is hypothesized that chiral analysis of nornicotine may be able to distinguish between tobacco-derived and synthetic nicotine samples by characterizing and comparing the ( R )/( S )-ratios of nornicotine and nicotine as they would be the same in SyN but different in TDN samples
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