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10.3945/an.110.1008 [DOI] [PMC free article] [PubMed] [Google Scholar] Wu G., Bazer F

A typical preventive protocol involves 0.25 mg daily for four to six weeks during preseason training or when significantly increasing training volume

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The 3-month minimum protocol applies here expect sleep improvements first, followed by recovery and aesthetic benefits, with body composition changes becoming noticeable around months 23