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Therefore, we aim to test a secondary hypothesis that baseline nicotine metabolite ratio (NMR) will moderate the experimental treatment effect, such that the benefit of dose titration will be greater in those participants who are rapid metabolizers of nicotine, and the final titrated dose they reach will be higher on average than the slow metabolizers

PMID: 31252671

Imperial Tobacco, one of the world's biggest cigarette firms, loses display battle Ministers say the ban is needed to protect future generations from the "devastating effects" of smoking

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