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Extending the scope of the Directive to include new products such as e-cigarettes, heated tobacco, and nicotine pouches

Manufacturers of flavored vape liquid will still be able to apply for FDA approval, a designation that brings with it a much higher level of regulatory oversight and would require the products to be dispensed by medical professionals instead of at gas stations and smoke shops

Promising results in animal studies and incipient clinical trials have made MSC therapy further increasingly recognizing the potential contribution of mitochondrial transfer from the MSCs as a potential mechanism of action (170, 171)