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Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation

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We use a modified form of AP designed by Beckwith and colleagues (Figure 3A) suggested a modest rise (~ 15%) in mean activity among replicate samples, but the sample-to-sample variation was large enough that statistical significance was not achieved ( p = 0.57)

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