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Duke once boasted he was "going to do with tobacco exactly what Rockefeller had done with oil. The social and economic impact of trusts and monopolies was a central political debate of the era, however, and just as Dukes control of the tobacco trade reached its apex in the early twentieth century, the tide began to turn

12 Diseases Caused by Smoking Each year, the American Cancer Society encourages smokers to quit smoking on the third Thursday of November

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"Tobacco industry lawyers actually influenced the content of his writings, suggesting to him things that he should comment on." They also, Petticrew says, spent a huge amount of money funding his research