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Therefore, providing an updated summary of the exposureresponse relationship between SHS and multiple adverse health outcomes, as well as innovatively quantifying the strength of the evidence supporting these relationships, is essential to continue to inform tobacco control policy, research funders and clinical recommendations and guide individual decisions related to smoking practices

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Compositional variations likely explain these differences: the high pH/additive contents of black shammah may accelerate oxidative darkening, whereas the fine particulates of DZRT could enable deep staining followed by leaching 18

Its even possible that the last time this nearly pristine pipe was smoked, maybe the only time, was shortly after it was sold