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Acknowledgements Research reported in this publication was supported by grant R01DA036493-02-S1 and R01DA036493-04-S1 from the National Institute on Drug Abuse of the National Institutes of Health

The Sensitive-C was developed by Olig Ag, in Germany, as an alternative to traditional cigarettes

Timiryazev Institute of Plant Physiology, Moscow, Russia Artem Alekseevich Fomenkov Department of Dermatology, Kobe University, Kobe, Japan Takeshi Fukumoto Department of Pathology, Federal University of Espirito Santo, Vitria, Brazil Blima Fux Department of Community Medicine and Family Medicine, All India Institute of Medical Sciences, Gorakhpur, India G