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Most people can get enough vitamin B12 in foods they eat already, such as fish, meat poultry, eggs, dairy products, and foods that are fortified with B12 (like some breakfast cereals)

Pickart and Margolinas 2018 review in Int J Mol Sci catalogs its regenerative and protective actions matrix remodeling, antioxidant and anti-inflammatory gene modulation, and wound-repair signaling but this is a review of largely preclinical and cell-based work (PMC6073405)

NNMT inhibition via 5-Amino-1MQ was associated with higher NAD+ levels, thereby influencing sirtuin activation and mitochondrial function