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Hair shedding has been reported during treatment and appears associated with weight reduction, not direct damage to hair follicles

Glutaminedependent changes in gene expression and protein activity

A305338 Rabbit monoclonal [ARC0630] antibody to Glutathione Synthetase for WB and ICC/IF

Thus, in a nutshell, it is possible that the initial DNA damage that predisposes melanocytes to malignant transformation and cytogenetic alterations that later promote actual malignant transformation of the initially transformed melanocytes may be driven by dysregulation in melanin biosynthesis and by the increased cellular content of melanin [10]