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Despite the fact that FDA has denied marketing authorization for millions of flavored e-cigarette products, several studies have shown that the number of e-cigarettes on the market has increased and that these products have gotten larger in volume, stronger in nicotine strength and cheaper to buy, the letter states

Additionally, another study of more than 3,500 high school students in Southern California found that flavored oral nicotine products (i.e., gum, lozenges, and gummies), which are often marketed as tobacco-free or tobacco leaf-free, were the second most popular nicotine products used among adolescents, after e-cigarettes

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The flavour profile of pipe tobacco, even in its natural state, is also more complex than cigarette tobacco