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Chronic exposure to nicotine could result in desensitization of nicotinic cholinergic receptors, thereby blocking potentiation of the nerve

As things were, A.B.C.s going rate for cigarette commercials run in prime time was forty thousand dollars a minute, and, looking ahead to the prospect of tobacco-company sponsorship for the 1970 professional-football season, the network was setting an asking price of sixty-five thousand dollars a minute for cigarette commercials run during the games