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Boosts Libido, Sexual Motivation, and Arousal: Research suggests that PT-141 enhances libido, sexual motivation, and arousal by targeting central neural circuits of desire through melanocortin receptor activation (MC3R/MC4R)

However, our study focuses specifically on pharmacological aspects of GLP-1R agonism, with prolonged incubations deliberately chosen to mimic in vivo drug exposure, and knockdown of both -arrestin isoforms to better approximate the response to exendin-phe1 and related agonists

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Body composition data from the SURMOUNT-1 DXA substudy showed approximately 75% of weight lost came from fat mass and 25% from lean mass