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[5] Systemic disorders [edit] Some systemic disorders are involved in angular cheilitis by virtue of their association with malabsorption and the creation of nutritional deficiencies described above

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10.1093/ajcn/nqaa430 Summary Keywords TMAO, L-carnitine, atherosclerosis, endoplasmic reticulum stress, vascular calcification Citation Wang B, Qiu J, Lian J, Yang X and Zhou J (2021) Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: From Mechanism to Therapy

Studies have examined NNMT inhibition in relation to cellular methylation balance, NAD metabolism, and broader metabolic signaling pathways