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This is the window of highest risk for self-harm and relapse, which is why supervised medical detox is strongly recommended as the first clinical step in stimulant addiction treatment

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Since increased pH of smokeless tobacco has been shown to enhance nicotine absorption through buccal mucosa (Tomar and Henningfield, 1997), it is reasonably expected that increased alkalinity of a premium cigar could also promote oral nicotine absorption, even if emitted smoke is not inhaled

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