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Besides well-known oxidants or electrophiles, such as H 2 O 2 , 4-hydroxynonenal, and diethyl maleate (DEM), which also possess cytotoxicity, only few Nrf2 activators have been found to be useful in clinical trials (Sun et al
Monitoring focuses on glucose, lipids, liver/kidney context, and muscle-stress context when training intensity is high
HCG-based diets have been around for decades, and their effectiveness is highly debated within the medical community
These observations suggest that GPX4 expression and ferrous iron levels are upregulated in anti-colorectal cancer drug-tolerant cells and could hence be therapeutic targets for the selective eradication of persister cells
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