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In Rel3 spheroid cells treated with the SU11274 there is also increased expression MUSASHI-1 along with an increase in Nestin, which can be also related to the increased cell motility, invasiveness and malignancy

Supporting this, data from our functional enrichment analysis of the transcriptome revealed notable upregulation of oxidative phosphorylation and the oxidative damage response in hepsin / mice treated with saline (data not shown)

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