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The stimulation of smoke-exposed epithelial cells with PAMPs, such as lipopolysaccharide (LPS) or dsRNA as well as exposure to human rhinovirus, nontypeable Haemophilus influenzae (NTHI), Staphylococcus aureus and Moraxella catarrhalis attenuated the in vitro production of potent pro-inflammatory mediators, in particular pathogen-induced neutrophil-mobilizing cytokines [136,153,154,155,156]

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This quality is essential because it means the wrap can endure the manipulation involved in rolling without succumbing to tears or unraveling