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By contrast, applying the simplified 20-year smoking duration guideline would capture over 80 percent of both Black and white participants who developed lung cancer in the Southern Community Cohort Study, and 64 percent of lung cancer patients in the Black Womens Health Study

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PMI, for example, has announced a significant ambition to build its future on smoke-free products, aiming for them to account for over 50% of total net sales by 2025

Second, pretreatment with nicotine does not fully capture the myriad of other psychoactive constituents that are present in tobacco leaves, combustible tobacco products, or e-cigarette vaping liquids, and further investigations are needed in order to characterize how these other psychoactive constituents interact with nicotine and fluoxetine