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Excess body fat can lead to chronic inflammation, insulin resistance, and hormonal imbalancesall of which can create an environment conducive to cancer development

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126,127 They comprise the following members: the serine/threonine protein kinases, PAR-1 ( = microtubule affinity-regulating kinase 2, MARK2, in vertebrates), and PAR-4 ( = Liver kinase B1, LKB1 or Serine/threonine-protein kinase 11, STK11, in vertebrates)