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He notes that e-cigarettes are marketed in ways that appeal to teens, with flavors such as grape, cotton candy and bubble gum

Fifty e-cigarette puffs was selected as an optimal controlled dose as it approximated the dose of nicotine delivered by the cigarette used in the study (~0.8 mg) based on machine yields of the e-cigarettes determined previously using a standardized Canadian Intense puffing protocol [20, 21]

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Some Companies Finding Ways to By-Pass Health Regulations The FDA cracked down on the creation of flavored e-cigs in 2020