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But it remains the case, as Simon Chapman points out , that e-cigarettes have yet to deliver on lofty promises of: rapid and spectacular migration from incontestably far more dangerous cigarettes, driven by an unprecedented consumer acceptable nicotine delivery system

A key element of the study was the validation of the Italian version of the Respiratory Symptom Experience Scale (IT-RSES), a sensitive clinical tool designed to detect early signs of respiratory distress in smokers

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doi: 10.1111/add.13757 2