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Approach to Payment Limit Calculations When Manufacturer's ASP Data is Not Available As described in the previous section, we determined that it is appropriate for CMS to provide additional guidance regarding how we will handle payment for drugs separately payable under Part B when the reported manufacturer's ASP for at least one NDC within the billing and payment code (that is, HCPCS code) of the drug is negative or zero (that is, has negative or zero manufacturer's ASP data)

These rankings were then used to allocate weights that would be applied to each factor when developing the HEIC

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