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Smoking can cause the following damage to the skin: skin cancer poor wound healing increased infection psoriasis hidradenitis suppurativa bags under the eyes drooping skin deep wrinkles and lines uneven skin tone dry skin While the exact reason behind these changes isnt well understood, most theories suggest premature aging from tobacco is caused by: poor blood flow a breakdown of elastic skin fibers an increase of cell-damaging particles called free radicals The appearance of smoking fingertips can vary from person to person, but it generally involves a yellow-brown stain on the tips of the thumb, index finger, and middle finger

The cytoplasmic side of p53s oncosuppressive activities