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(2) CMS will match the covered Part D drugs identified in the PDE data with application numbers using FDA sources to determine whether each covered Part D drug is a drug or biological approved under an NDA under section 505(c) of the FD&C Act, approved under an ANDA under section 505(j) of the FD&C Act, or licensed under a Biologics License Application (BLA) under section 351 of the PHS Act, as of the first day of the applicable period

This means the heart needs to pump harder to deliver blood around the body, increasing blood pressure

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In fact, smokeless tobacco contains 28 cancer-causing agents, making it a very unsafe alternative to cigarettes