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This causes airtight cases to form an intense internal vacuum

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In addition, because strict workplace smoking restrictions encourage some smokers to quit and others to reduce the number of cigarettes smoked,77 a trend that is reversed when restrictions are relaxed,2 79 passage of the initiative would have actually increased smoking and exposure to secondhand smoke.80 While Philip Morris's public statements did not emphasize the potential of the initiative to protect tobacco profits, the company explicitly presented the initiative as a way for tobacco retailers to protect their business: The adverse impact on retail cigarette sales would be immediate [without the initiative]

It can cause hypertension, arrhythmia, and atherosclerosis