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Cigarette smoke disrupts gutlung axis communication through microbial metabolite alterations driving pulmonary inflammation and cancer progression Interestingly, accumulating investigations demonstrate that cigarette smoke distorts gutlung axis communication by altering microbial metabolite profiles, creating a pro-inflammatory milieu that fuels pulmonary deterioration in COPD and promotes oncogenic niches in lung adenocarcinoma (LUAD)

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He explains that when smoking decreases in affluent Western countries due to heavy taxation, tobacco companies make up for lost revenue by selling products at vastly reduced prices in the developing countries, which encourages children and teens to take up smoking