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FDAs review determined that the claim proposed by the company in its application is supported by scientific evidence, that consumers understand the claim and appropriately perceive the relative risk of these products compared to cigarettes, and that the modified risk products, as actually used by consumers, will significantly reduce harm and the risk of tobacco-related disease to individual tobacco users and benefit the health of the population as a whole

The score is calculated: A score between 0 and 2 suggests very low dependency

22 From the blood, nicotine quickly diffuses into breast milk