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Well how about a nice little infographic from Cancer Research UK That seems pretty clear to us

While individual contributions of aforementioned carcinogens may never be known due to the complexity of the system, there is little doubt that their removal from cigarette smoke (if that was even a possibility) would substantially decrease the negative consequences of inhalation

When someone drinks alcohol during pregnancy, the alcohol in the blood quickly passes through the placenta and the umbilical cord to the baby

This trend is especially concerning for youth, who are more price-sensitive and may be more likely to use cheaper, high-nicotine products