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The correlations (R 2 ) between cytotoxicity and the total number of flavor chemicals in a refill fluid or the total concentration of flavor chemicals in each product were 0.42 and 0.54, respectively

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[4] [5] [21] [19] Scientific conclusions [edit] According to the 2004 Surgeon General's report, "Smoking cigarettes with lower machine-measured yields of tar and nicotine provides no clear benefit to health." [22] The tobacco industry's own internal documents also reveal that cigarette manufacturers are aware of the difference between machine-measured levels of nicotine and tar, and those actually inhaled by smokers

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