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Pregnant or breastfeeding women should consult a healthcare provider before use

Many direct or indirect markers of oxidative stress, including malondialdehyde, thiobarbituric acid, and glutathione disulfide, have been found in urine, plasma, sputum, and BAL fluid of patients with asthma, and the level of the markers correlated with the severity of the disease [6769]

A 2006 study, published in the June 17 edition of The Journal of European Child and Adolescent Psychiatry, shows a significant reduction of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in children after supplementing with Pycnogenol every day for one month

Jackson AL, Loeb LA: The contribution of endogenous sources of DNA damage to the multiple mutations in cancer