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Since randomized trials and prospective cohort designs on this topic are not practical given the ethical issues and the need for a large study population with extended follow-up, there is a need for well-designed retrospective studies despite the inherent limitations from recall bias and unmeasured confounding factors
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However, investors should note that the dividend payout ratio currently stands in excess of 400%, which is certainly unsustainable in the long run
In spite of the possibly poisonous nature, or maybe because of its qualities, the plant has been used for pleasure, ceremonies, and medicine by native people
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