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doi: 10.1007/s11010-021-04193-3

According to Yucca Health's safety information pages, the most common side effects include: Gastrointestinal Effects: Nausea (most common, especially early on) Diarrhea Constipation Vomiting Indigestion and abdominal discomfort Feeling full quickly after eating Other Common Effects: Headache Fatigue Dizziness Managing Side Effects: Most patients find that nausea and gastrointestinal symptoms improve as the body adjusts to the medication

This mechanism is well-documented: a peer-reviewed review in Drugs evaluating Sermorelins use in the diagnosis and treatment of growth hormone deficiency confirms it works by stimulating endogenous pituitary GH release through the GHRH receptor

We had been making mathematical models of different parts of OCM since 2002, so it was relatively straightforward to put in the effects of estradiol and testosterone into the models and find out the male-female differences in OCM, and this led to Project 1