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Tobacco use is continued despite knowledge of having a persistent or recurrent physical or physiological problem that is likely to have been caused or exacerbated by tobacco

Cigarette paper is one of the primary factors that affect the flavor and quality of cigarettes in addition to the tobacco leaves

Combination long-acting + short-acting NRT: provides a stable baseline nicotine level from the sustained release transdermal patch with immediate release nicotine gum, lozenge, nasal spray or oral inhaler

However, it has been unclear whether smoking could be a factor in causing such problems or is simply a form of self-medication among those already living with poor mental health