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The main pharmacokinetic indices altered in smokers compared to non-smokers indicated that the effective concentration of the drug at plasma level was achieved lower in smokers than in non-smokers at the same dose administered and, in general, a reduction in the bodys exposure to the drug

On the other hand, according to neighborhood effect theory, the social and educational environment shapes individual behaviors and norms 10,11

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Some studies have highlighted cases of vaping-induced pneumonitis, or e-cigarette or vaping use associated lung injury (EVALI) 9,10 , as well as a higher likelihood of developing asthma 11 , however there is currently no concrete evidence that e-cigarettes cause respiratory disease 12