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Methods Study design STEP-HFpEF (NCT04788511) was a randomized, international, double-blind, placebo-controlled trial that examined the efficacy and safety of semaglutide 2.4 mg once weekly compared to placebo in patients with the obesity phenotype of HFpEF without diabetes 11

It provides context for baseline metabolic traits and should be interpreted with your provider alongside clinical markers, lifestyle, and medication trial data to inform personalized decisions

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Micronuclei are small nuclei-like structures containing chromatin encapsulated by the nuclear envelope, which arise from chromosomal instability (203)