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Whilst semaglutide has demonstrated cardiovascular benefits in clinical trials for people with type 2 diabetes, the interaction between these opposing cardiovascular profiles is not well studied
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The exclusion criteria were: a) studies involving cell culture experiments to examine the effects of GLP-1-based therapies on atherosclerosis markers
The authors compared changes in glycemic control and BMD with and without conversion from DPP-4 inhibitor to GLP-1 receptor agonist for 3 years and observed that patients who switched to the latter had greater decline in lumbar BMD than controls regardless of weight loss [12, 61]
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