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Statistical analysis For each phenotype (n = 313), we created and characterised a disease cohort using descriptive statistics of key demographic factors (e.g., sex, assessment centre country, socioeconomic deprivation/Townsend score), and lifestyle risk factors (e.g., smoking status)

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Although he lived in New York City for much of his adult career, Ryan was perhaps the greatest benefactor of the Roman Catholic Diocese of Richmond in the decades before the Great Depression