, Gd 3+ , Mg 2+ , Mn 2+ , Mn 3+ , Mn 4+ , Si 4+ "above and herein is equivalent to the expression:" each occurrence of M independently represents an ion metal selected from the group consisting of Fe, Fe 3+ , Zn 2+ Ti 3+ Ti 4+ , Zr 2+ , Zr 4+ Ca 2+ Cu 2+ , Gd 3+ , Mg 2+ , Mn 2+ , Mn 3+ , Mn 4+ , Si 4+ .Cu 2+ , Gd 3+ , Mg 2+ , Mn 2+ , Mn 3+ , Mn 4+ , Si 4+ "
The Agilent 6530 Q-TOF was used to identify and analyze levels of citrate, -ketoglutarate, fumarate, malate, and ceramide, which was confirmed by comparing retention times and tandem mass spectrometry data with standard compounds
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