The cardiometabolic data also reinforce the emerging understanding that incretin-based therapies produce benefits beyond weight loss itself likely through direct receptor-mediated effects on hepatic metabolism, vascular inflammation, and lipid handling
Whether they gave the peptide body-wide or delivered it directly to the kidneys, it reduced the movement of immune cells into the kidneys, resolved inflammation and damage and improved kidney function, without increasing blood pressure, they report in the journal Kidney International
Kravetz L, Leeman S, Regev T et al (2025) The effect of glucagon-like peptide-1 agonists on ocular parameters in idiopathic intracranial hypertension patients: a retrospective study
Testing reveals variants in genes like GLP1R, GIPR, and FTO that influence how your body responds to metabolic therapies