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Methods Sample and recruitment This cross-sectional study used a Chinese research firm to collect survey data from adults (aged 18 and older) living in Beijing, Shanghai, and Shenzhen during 2017

F17 Nicotine dependence Excludes1: history of tobacco dependence (Z87.82) tobacco use NOS (Z72.0) Excludes2: tobacco use (smoking) during pregnancy, childbirth, and the puerperium (O99.33-) toxic effect of nicotine (T65.2-)

It increases blood pressure, speeds up the heart rate, narrows the breathing tubes making it harder to breath and hyper stimulates the brain