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In addition, inflammation affects the production of reactive nitrogen species (RNS), the high expression state of nitricoxide synthase produces excess -NO, which can alter the homeostasis of normal intestinal epithelial cells, ROS/RNS levels are involved in tumour cell proliferation, survival and metastasis by inducing DNA mutations, creating genomic instability, silencing tumour suppressor genes or acting as a signalling molecule [24-27]

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For example, the binding of HSA to polyunsaturated fatty acids and sterols may prevent lipid peroxidation

I had used Ozempic for about a year and so I had my own reference point