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Mutation Research/Genetic Toxicology and Environmental Mutagenesis 774:816

For many years, falsified medicines have been traded worldwide

Note: Not recommended for individuals with a history of cancer

TMAO-induced inflammation and endothelial dysfunction in human umbilical vein endothelial cells (HUVECs) can be reversed by treatment with the ROS inhibitor N-acetylcysteine (NAC) or by siRNA-mediated knockdown of NLRP3, suggesting that TMAO exerts its pro-inflammatory effects via the ROS/NLRP3 inflammasome [146]