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Hallmark gene set analysis reveals pathways associated with interferon-alpha responses and DNA damage repair are downregulated while pathways associated with sterile inflammation are upregulated in NHBECs after DA vapor exposure To further characterize transcriptional profiles, we applied the pre-ranked GSEA to 50 Hallmark gene sets with well-defined biological mechanisms and coherent expression levels

This can be due to various factors, including medications, age-related health conditions and hormonal changes such as a decrease in testosterone levels and an increase in estrogen levels

During his half-century in television, Peter Lassally (who died last Sunday at age 93) played producer and confidant to late-night hosts David Letterman, Craig Ferguson, Tom Snyder, and Johnny Carson