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During the process of research & development, imipramine was synthesized as a structural analog of chlorpromazine

Moreover, CSD can be brought on by variations in the concentrations of intracellular and extracellular ions, which can result in brief oxidative stress and the release of neurogenic inflammatory factors

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Melanin is important for skin homeostasis and when melanogenesis is triggered by UV radiation exposure, a tanning response is important for indicating a stress response signal