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The search details are shown in Supplementary Table 1, meantime the inclusion criteria were as follows: (i) patients with PCOS, (ii) patients with the treatment of carnitine supplementation, (iii) patients with body weight information, (iv) patients with exact doses and durations of carnitine supplementation, and (v) patients with the control group

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[3] The British Society for Haematology guidelines emphasise that the response to treatment should be monitored through clinical assessment and blood count testing, rather than routine measurement of B12 levels after treatment has started