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The situation in these two countries, which introduced moderate measures and increased the tax progressively, varies greatly from that of Chile that has the most expensive cigarette package in Latin America at $ 5.50 dollars
You just kind of do it over time
For examples of other successful state and local efforts to limit tobacco exposure to youth in the retail environment, see our Point-of-Sale Fact Sheet and Policy Resource
Furthermore, prolonged CS exposure induces FIS1 expression and reduction of MFN, resulting in mitochondrial fragmentation with enhanced ROS [39, 41]
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