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Assessments include (1) demographic information, (2) smoking history and a timeline-follow-back interview to assess tobacco use including smoking quantity and frequency such as number of cigarettes per day and number of years smoked, (3) expired breath carbon monoxide (CO) measured in parts per million, (4) a urine sample for screening for cotinine, pregnancy, and recent drug use, and (5) a health interview to rule out high-risk participants with unstable conditions